The following is a non-exhaustive list of articles by Dr. Nemer published in a variety of high impact scientific journals (latest update July 23, 2010).
Rysä J, Tenhunen O, Serpi R, Soini Y, Nemer M, Leskinen H, Ruskoaho H. GATA-4 is an angiogenic survival factor of the infarcted heart. Circ Heart Fail. 2010 May;3(3):440-50.Hayek S, Nemer M. Cardiac Natriuretic Peptides: From Basic Discovery to Clinical Practice. Cardiovasc Ther. 2010 Apr 23. [Epub ahead of print]
Koshiba-Takeuchi K, Mori AD, Kaynak BL, Cebra-Thomas J, Sukonnik T, Georges
RO, Latham S, Beck L, Henkelman RM, Black BL, Olson EN, Wade J, Takeuchi JK,
Nemer M, Gilbert SF, Bruneau BG. Reptilian heart development and the molecular
basis of cardiac chamber evolution. Nature. 2009 Sep 3;461(7260):95-8.
Kyrönlahti A, Rämö M, Tamminen M, Unkila-Kallio L, Butzow R, Leminen A, Nemer
M, Rahman N, Huhtaniemi I, Heikinheimo M, Anttonen M. GATA-4 regulates Bcl-2
expression in ovarian granulosa cell tumors. Endocrinology. 2008
Nov;149(11):5635-42
Georges R, Nemer G, Morin M, Lefebvre C, Nemer M. Distinct expression and
function of alternatively spliced Tbx5 isoforms in cell growth and
differentiation. Mol Cell Biol. 2008 Jun;28(12):4052-67
Rivard K, Paradis P, Nemer M, Fiset C. Cardiac-specific overexpression of the
human type 1 angiotensin II receptor causes delayed repolarization. Cardiovasc
Res. 2008 Apr 1;78(1):53-62
Nemer M. Genetic insights into normal and abnormal heart development. J Cardiovasc Pathol, 2008, 17(1), 48-54
Majalahti T, Suo-Palosaari M, Sarman B, Hautala N, Pikkarainen S, Tokola H, Vuolteenaho O, Wang J, Paradis P, Nemer M, Ruskoaho H. Cardiac BNP gene activation by angiotensin II in vivo. Mol Cell Endocrinol, 2007, 273(1-2):59-67
Nemer M, Horb ME. A role for the KLF family of transcriptional regulators in cardiomyocyte proliferation and differentiation. Cell Cycle 2007, 6(2):117-121
1Lavallée G, 1Andelfinger G, Nadeau M, Lefebvre C, Nemer G, Horb M, Nemer M. The Kruppel-like transcription factor KLF13 is a GATA-4 collaborator for heart development. EMBO J 2006, 25:5201-5213.
1These authors contributed equally to the work
Nemer M, Dali-Youcef N, Wang H, Aries A, Paradis P. Mechanisms of angiotensin II-dependent progression to heart failure. 2006 Heart failure: molecules, mechanisms and therapeutic targets. John Wiley & Sons Ltd, Chichester UK, Novartis Foundation Symposium 274, 2006, p 58-72
Nemer G, Fadlalah F, Usta J, Nemer M, Dbaibo G, Obeid M, Bitar F. A novel mutation in the GATA4 gene in patients with tetralogy of Fallot. Hum Mutat 2006, 27(3):293-294
Wang J, Paradis P, Aries A, Komati H, Lefebvre C, Wang H, Nemer M. Convergence of PKC and JAK-STAT signaling on transcription factor GATA-4. Mol Cell Biol 2005, 25 (22), 9829-9844
Debrus S, Rahbani L, Marttila M, Delorme B, Paradis P, Nemer M. The zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling. Mol Cell Biol 2005, 25(19), 8669-8682
Morin S, Pozzulo G, Robitaille L, Cross J, Nemer M. MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters. J Biol Chem 2005, 280(37):32272-32278
Takeuchi JK, Koshiba-Takeuchi K, Mileikovskaia M, Mori AD, Arruda EP, Gertsenstein M, Georges R, Davidson L, Mo R, Hui CC, Henkelman RM, Nemer M, Black BL, Nagy A, Bruneau BG. Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motor neuron development. Development 2005, 132(10), 2463:2474
Temsah R, Nemer M. GATA factors and transcriptional regulation of cardiac natriuretic peptide genes. Regul Pept 2005, 128 (3), 177-185
Anne Aries, Pierre Paradis, Chantal Lefebvre, Robert J. Schwartz, and Mona Nemer. Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity. Proc Natl Acad Sci USA 2004, 101: 6975–6980
McBride K, Charron F, Lefebvre C, Nemer M. Interaction with GATA transcription factors provides a mechanism for cell-specific effects of c-Fos. Oncogene 2003,22:8403-8412
Pikkarainen S, Tokola H, Majalahti-Palviainen T, Kerkelä, Hautala N, Bhalla SS, Charron F, Nemer M, Vuolteenaho O, Ruskoaho H. GATA-4 is a nuclear mediator of mechanical stretch-activated hypertrophic program. J Biol Chem 2003, 278:23807-23816
Nemer G, Nemer M. Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and –6. Developmental Biol 2003, 254:131-148
Nemer G, Nemer M. Cooperative interaction between GATA-5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells. Development 2002, 129:4045-4055
Brewer A, Nemer G, Gove C, Rawlins F, Nemer M, Patient R, Pizzey J. Widespread expression of an extended peptide sequence of GATA-6 during murine embryogenesis and non-equivalence of RNA and protein expression domains. Mech Dev 2003, 119 Suppl1:S121-129
Suo M, Hautala N, Foldes G, Szokodi I, Toth M, Leskinen H, Uusimaa P, Vuolteenaho O, Nemer M, Ruskoaho H. Posttranscriptional Control of BNP Gene Expression in Angiotensin II-Induced Hypertension. Hypertension 2002, 39:803-8
Nemer G, Nemer M. Regulation of heart development and function through combinatorial interactions of transcription factors. Ann Med 2001, 33:604-610
Marttila M, Hautala N, Paradis, P, Toth M, Vuolteenaho O, Nemer M, Ruskoaho H. GATA-4 mediates activation of the B-type natriuretic peptide gene expression in response to hemodynamic stress. Endocrinology 2001, 142:4693-4700
1Bruneau BG, 1Nemer G, Schmitt, JP, Charron F, Robitaille L, Caron S, Conner DA, Gessler M, 2emer M, Seidman CE, 2Seidman JG. A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 2001, 106:709-721.
1These authors contributed equally to the work. 2Co-senior authors
Charron F, Tsimiklis G, Robitaille L, Arcand M, Meloche, S, Nemer M. Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA. Genes Dev 2001, 15:2702-2719
1Morin S, 1Paradis P, Aries A, Nemer M. SRF/GATA ternary complex required for nuclear signaling by a G-protein coupled receptor. Mol Cell Biol 2001, 21:1036-1044.
1These authors contributed equally to the work
McBride K, Nemer M. Regulation of the ANF and BNP promoters by GATA factors: lessons learned for cardiac transcription. Can J Physiol Pharmacol 2001, 79:673-681
Bhalla SS, Robitaille L, Nemer M. Cooperative activation by GATA-4 and YY1 of the cardiac B-type natriuretic peptide promoter. J Biol Chem 2001, 276:11439-11445
Charron F, Morin S, Nemer M. Interactions entre les facteurs MEF2 et GATA dans la différenciation cellulaire. Médecine/sciences 2001, 17:98-102
Belaguli NS, Sepulveda JL, Nigam V, Charron F, Nemer M, Schwartz RJ. Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators. Mol Cell Biol 2000, 20:7550-7558
Fotheringham J, Xu FY, Nemer M, Kardami E, Choy PC, Hatch GM. Lysophosphatidylethanolamine acyltransferase activity is elevated during cardiac cell differentiation. Biochim Biophys Acta 2000, 1485:1-10
Morin S, Charron F, Robitaille L, Nemer M. GATA-4-dependent recruitment of the MEF2 proteins to target promoters. EMBO J, 2000, 19:2046-2055
Xu FY, Kardami E, Nemer M, Choy PC, Hatch GM. Elevation in phosphatidylethanolamine is an early but not essential event for cardiac cell differentiation. Exp Cell Res 2000, 256:358-364
Paradis P, Youcef-Dali N, Paradis FW, Thibault G, Nemer M. Overexpression of angiotensin II type 1 receptor in cardiomyocytes induces cardiac hypertrophy and remodeling. Proc Natl Acad Sci USA, 2000, 97:931-936
In the Media:
Chimiothérapie et dysfonction cardiaque: percée montréalaise. News, Radio-Canada.ca, April 22, 2004
Percée dans le traitement du cancer - April 21st 2004, Dr. Nemer explains the role of a cardioprotective protein
Cancer: importante percé montréalaise. LaPresse, Montréal, April 21, 2004
Percée dans le domaine de la chimiothérapie. iForum, Université de Montréal, Aprl 19, 2004
Mona Nemer, personnalité de la semaine, LaPresse, May 2, 2004
Interview in C'est bien meilleur le matin on May 3rd 2004 at 6h45 (format MP3)
Interview in Matin Express on May 3rd 2004 at 8h40 (format WMV)